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Vaccine boosters could be necessary as soon as the fall

The first Americans to be vaccinated against the coronavirus could require a third "booster" shot as early as September, the CEOs of Pfizer and Moderna told Axios.

Driving the news: “The data that I see coming, they are supporting the notion that likely there will be a need for a booster somewhere between 8 and 12 months," Pfizer CEO Albert Bourla said yesterday during an Axios event.


That means some Americans could need a booster as soon as September or October, he added.

State of play: Only time will tell how long protection from the first two vaccine doses will last, but there's no evidence yet that it's fading. Even if protection does begin to fade — which is common among vaccines — it won't happen overnight.

  • And as the virus continues to spread around the world, it’s possible that vaccine-resistant variants could eventually emerge. (The existing vaccines are highly effective against the variants currently circulating in the U.S.)

What they're saying: "I think we will almost certainly require a booster sometime within a year or so after getting the primary [shot] because the durability of protection against coronaviruses is generally not lifelong," NIAID director Anthony Fauci told Axios' Mike Allen at the same event.

  • "I think as a country we should rather be two months too early, than two months too late with outbreaks in several places," Moderna CEO Stephane Bancel wrote in an email.
  • "People at highest risks (elderly, healthcare workers) were vaccinated in December/January," he added. "So I would do [a] September start for those at highest risk."

The other side: Experts caution to consider the drug companies' predictions in context with their broader business goals.

  • "It’s not proven that we need boosters yet. Whereas it’s appropriate to plan for boosters, you’ve got to look at whether there’s a corporate agenda behind this," said Cornell professor and virologist John Moore.
  • “As of now, we don’t have any evidence that protective immunity has dropped to a troubling point, and certainly not for people immunized in December, January, February," he added. “It's hard to say where we will be in November because right now it’s May.”

The bottom line: Even if you received your first shot in December, you don't need to worry that you'll wake up tomorrow having lost all of your immunity.

  • “Personally, if I was in that situation, I wouldn’t be worrying about it — not yet. But I would want to see that data later in the year," Moore said.
  • The decline in protection would be gradual, and researchers around the world are gathering data on the subject through clinical trials and real-world evidence.

Reports: Trump DOJ subpoenaed Apple for records of WH counsel Don McGahn

Apple told former Trump administration White House counsel Don McGahn last month that the Department of Justice subpoenaed information about accounts of his in 2018, the New York Times first reported Sunday.

Why it matters: Although it's unclear why the DOJ took the action, such a move against a senior lawyer representing the presidency is highly unusual.

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Pelosi demands Barr and Sessions testify on data subpoenas she says go "beyond Richard Nixon"

House Speaker Nancy Pelosi (D-Calif.) told CNN Sunday that former Attorneys General William Barr and Jeff Sessions should testify before Congress on reports that the Trump-era Department of Justice seized Democrats' and journalists' data records.

Driving the news: DOJ Inspector General Michael Horowitz announced Friday an internal investigation into the matter, and Pelosi expressed disbelief to CNN's Dana Brash at assertions that neither Barr nor Sessions knew of probes into lawmakers.

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Shipping giant CEO says business have to avoid global politics

The CEO of the world's largest container-shipping company cautions that international firms have to be careful of taking political stances.

  • What they're saying: "We cannot run a global business if we start to have views on politics in every single country that we are in," Maersk CEO Søren Skou tells "Axios on HBO."
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Chamber of Commerce CEO Suzanne Clark defends overture to Democrats

U.S. Chamber of Commerce president and CEO Suzanne Clark told me on "Axios on HBO" that the business group was right to endorse vulnerable House Democrats last year, despite the flak that resulted from Republicans.

  • Clark, who took over the top job in March, said those House Democrats "had really helped push business's number one priority, which was the free trade agreement with Canada and Mexico, over the finish line."
  • "All of the Republicans that we work with on tax, on regulation — those people are really, really important to us," she added: "So we have to be willing to have a different coalition on every issue."
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Nuclear watchdog: “Essential” to have deal with Iran

The head of the International Atomic Energy Agency tells "Axios on HBO" that it's "essential" to have a nuclear deal with Iran because otherwise "we are flying blind."

Driving the news: Director-General Rafael Mariano Grossi sat down with "Axios on HBO" at IAEA headquarters in Vienna, ahead of Iran's June 18 presidential election and a June 24 extension on negotiations seeking to restore curtailed surveillance of Iranian nuclear sites and salvage the 2015 deal.

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U.N. ambassador Thomas-Greenfield sees tough Putin summit

Photo: "Axios on HBO"

Ambassador Linda Thomas-Greenfield, U.S. ambassador to the U.N., told me on "Axios on HBO" that President Biden will be candid, frank — and tough — during this week's summit with Russian President Vladimir Putin.

  • "The president will make clear to the Russians that they cannot harbor cyber terrorists and criminals in their country and not be held accountable for it," she added. "And they need to take the responsibility for dealing with this issue."
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Dems’ go-it-alone approach faces big hurdles as left’s frustrations spill over

If a bipartisan group of lawmakers fails to strike a deal on the infrastructure proposal it's negotiating with the White House, ramming through a package using the partisan reconciliation process isn't a guaranteed solution.

Why it matters: Getting 51 Democratic votes would be a long, uphill battle. And moderates within the party are balking at the cost of President Biden's spending — even as progressives openly lament that the "transformational" change they seek is slipping out of reach.

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America's U.N. ambassador: "I will always push for women to be part of negotiation teams"

Linda Thomas-Greenfield, U.S. ambassador to the U.N., has argued over her 39-year diplomatic career that educating and empowering women and girls is an investment in peace and security for their nations.

  • "I will always push for women to be part of negotiation teams," she told me in the State Department Treaty Room, during an interview for "Axios on HBO."
  • "I notice ... when they're not in the room. ... Sometimes I'm the only one," she added with a laugh. "And I will call it out."
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