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The billion-dollar COVID booster discussion

Pfizer said yesterday that it expects to sell nearly $34 billion worth of coronavirus vaccines this year — and there could be billions more behind that, if people who have gotten the shot ultimately need boosters.

Why it matters: It's unclear whether, when and for whom a coronavirus vaccine booster will be necessary. Pfizer has a lot of money riding on those answers, and executives are already making the case that many Americans will need a third dose.


What they're saying: Pfizer released new data, not yet peer-reviewed, that suggests the vaccine's efficacy diminishes over time — from 96% in the first two months after receiving the second dose, to 84% after four months.

  • Reduced efficacy could mean more transmission of the virus.
  • "We are very, very confident a third dose, a booster, will take up the immune response to levels that will be enough to protect against the Delta variant," Pfizer CEO Albert Bourla told CNBC yesterday.

Yes, but: The same data show the vaccine was still 97% effective in preventing severe disease, across a full six months of monitoring.

  • Those findings reinforce the FDA and CDC stances that people may not need booster shots at this time.

By the numbers: Pfizer increased its sales estimates yesterday for the doses it has already committed to sell. The company expects those sales to total $33.5 billion this year, almost a 30% jump from its previous estimates — without accounting for sales of any potential boosters.

What's next: "The [vaccine sales] numbers are going to be much higher," Bernstein analyst Ronny Gal wrote to investors, estimating Pfizer's sales could be as high as $43 billion this year.

  • "We expect total sales growth will slow over the next 12 months as COVID-19 vaccine demand shifts toward emerging markets where pricing is lower," analysts at Morningstar wrote about Pfizer. However, "potential upside exists if larger demand for boosters emerges."

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Dixie Fire now 2nd largest wildfire in California history

As wildfires rage across the West, California's Dixie Fire has grown to more than 463,000 acres as of Sunday, making it the second largest wildfire in the state's history, a representative from Cal Fire told Axios.

Why it matters: The Dixie Fire, which stretches across several counties in northern California, is currently the biggest wildfire burning in the country. As of Saturday evening, three people remain missing.

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The post-pandemic fight for your workout

The gym industry, battered by a year of pandemic-related closures and customer losses, faces an added hurdle as it looks to recover: the rise of home workout technology.

The big picture: Health clubs in the U.S. saw revenue drop by more than half last year. Meanwhile, Americans working at home started getting in shape there as well, Peloton sold bikes as fast as it could make them, and Apple started selling fitness subscriptions.

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