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Malaria vaccine from Oxford's COVID-19 team highly effective in early trials

A malaria vaccine developed by Oxford University was found to have "high-level efficacy" in phase II trials, according to a pre-print study released on Friday.

Why it matters: Malaria kills over 400,000 people a year, more than half of them children under the age of 5. Deaths have fallen in half over the past 20 years thanks to investment in prevention and drugs, but a truly effective malaria vaccine would represent one of the greatest victories in the history of public health.


Details: The vaccine was found to be 77% effective, becoming the first to surpass the World Health Organization's goal of having a vaccine with at least 75% efficacy by 2030, Oxford University said in a statement.

  • "[N]o serious adverse events related to the vaccine" were noted, according to Oxford.
  • The trial included 450 participants between the ages of 5 and 17 months, and lasted over 12 months.
  • The participants were split into three groups: Those who received a higher dose were found to be 77% less likely to develop malaria, while those with a lower dose recorded 71% efficacy. The rest of the participants received a rabies vaccine as the control group.

What's next: "Larger trials in nearly 5,000 children between the ages of five months and three years will now be carried out across four African countries, to confirm the findings," BBC writes.

Worth noting: This study is not yet peer-reviewed. Oxford's Jenner Institute is the same that successfully developed the AstraZeneca coronavirus vaccine.

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Elon Musk suspends Tesla purchases with bitcoin

Consumers can no longer buy Tesla vehicles with bitcoin, CEO Elon Musk announced on Twitter Wednesday.

What he's saying: Musk cited the environmental concerns associated with bitcoin — the cryptocurrency has a massive carbon footprint — as his reasoning behind Wednesday's decision.

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IEA analysis charts "narrow" pathway to Paris climate goal

The pathway for transforming global energy systems to reach net-zero emissions by 2050 is "narrow but still achievable" and demands unprecedented acceleration away from fossil fuels, an International Energy Agency report published Tuesday concludes.

Why it matters: It provides detailed analysis and estimates of what's needed for a good shot at limiting temperature rise to 1.5°C above preindustrial levels — the Paris Agreement benchmark for avoiding some of the most damaging effects of climate change.

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Biden issues executive order that requires new steps on climate-related financial risk

President Biden issued an executive order Thursday that directs agencies government-wide to launch or expand efforts to analyze and lessen economic risks stemming from climate change.

Why it matters: The move signals growing concerns that the government lacks sophisticated understanding of how global warming creates new or growing jeopardy for financial and government institutions, consumers and other parties.

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Pelosi announces select committee to investigate Jan. 6 Capitol riot

Speaker Nancy Pelosi (D-Calif.) announced Thursday that she will create a House select committee to investigate the deadly Jan. 6 Capitol riot.

Why it matters: The creation of a single Democratic-controlled special committee, which will consolidate several House investigations, comes after Senate Republicans blocked a bill that would have established a bipartisan 9/11-style commission.

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