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Pfizer says COVID-19 vaccine 91.3% effective through 6 months

Pfizer and BioNTech announced Thursday that their COVID-19 vaccine was 91.3% effective at protecting against symptomatic disease up to six months after the second dose, with no serious safety concerns, according to an updated analysis of clinical trial results.

Why it matters: Real-world and trial data continue to indicate that the vaccine is highly effective, especially against COVID-19 hospitalization and death. The companies said updated trial results showed the vaccine offered 100% protection against severe disease as defined by the CDC, and 95.3% as defined by the FDA.


Details: 927 symptomatic COVID-19 cases were detected among the trial's 46,307 participants — 850 of which came from the placebo group and 77 of which came from the vaccine group.

  • 32 cases of severe disease as defined by the CDC were observed in the placebo group, and none were observed in the vaccine group.
  • Researchers found no serious safety concerns in trial participants up to six months after the second dose, and the side effects were consistent with previously reported results.

What they're saying: “It is an important step to further confirm the strong efficacy and good safety data we have seen so far, especially in a longer-term follow-up,” said BioNTech co-founder and CEO Ugur Sahin.

  • “These data also provide the first clinical results that a vaccine can effectively protect against currently circulating variants, a critical factor to reach herd immunity and end this pandemic for the global population," he added.

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House Judiciary chairman accuses Attorney General Barr of undermining democratic norms

House Judiciary Chairman Jerry Nadler (D-N.Y.) painted the integrity of the Justice Department as "more at risk than at any time in modern history" in opening remarks at a hearing for Attorney General Bill Barr Tuesday, accusing him of shielding President Trump from responsibility and eroding democratic norms.

Why it matters: The hearing, which focuses on the DOJ's alleged politicization under Barr, is the attorney general's first time appearing before the committee. Barr in his own remarks accused the committee's Democrats of trying to discredit him over his investigations into the origins of the FBI's Russia probe.

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The pandemic is getting worse again

Data: The COVID Tracking Project, state health departments; Note: Due to a database error, Missouri had a 3 day gap in reporting from Oct. 11-13; Map: Andrew Witherspoon/Axios

Every available piece of data proves it: The coronavirus pandemic is getting worse again, all across America.

The big picture: As the death toll ticks past 212,000, at a moment when containing the virus ought to be easier and more urgent than ever, we are instead giving it a bigger foothold to grow from.

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Fauci says transition delay harmful to public health as COVID-19 cases surge

NIAID Director Anthony Fauci said on CNN's "State of the Union" Sunday that President Trump's refusal to cooperate with President-elect Biden's transition team hurts public health as coronavirus cases surge across the country.

The state of play: As President Trump refuses to concede the election to President-elect Joe Biden, General Services Administration Administrator Emily Murphy has not signed documents declaring Biden the apparent winner, preventing the president-elect's agency review teams from having access to the information they need in order to get to work.

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Biden to unveil executive actions on gun violence prevention

President Biden is expected to present a series of executive actions on guns Thursday, including directing his Justice Department to tighten regulations on purchases of so-called “ghost guns."

Why it matters: The president has faced increased pressure from Democrats and gun violence prevention groups to act on the issue following a series of recent high-profile gun tragedies across the U.S.

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