President Biden told ABC News Tuesday that if allegations of sexual misconduct against New York Gov. Andrew Cuomo (D) are confirmed, he should resign.

Why it matters: These are Biden's strongest words yet on his longtime friend and ally. Only two days ago, the president said he'd wait for the outcome of an investigation into the harassment and misconduct allegations leveled against Cuomo before commenting on whether the governor should resign.

• The only Democratic figure who could likely persuade Cuomo to resign is Biden, per Axios' Jonathan Swan.

Of note: Cuomo continues to deny all allegations leveled against him.

What they're saying: In his interview with Biden, ABC News' George Stephanopoulos said, "I know you said you want the investigation to continue. If the investigation confirms the claims of the women, should he resign?"

• Biden replied: "Yes. I think he'll probably end up being prosecuted, too."

Editor's note: This a breaking news story. Please check back for updates.